Digital Medicine by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9783319982168
Publisher: Springer International Publishing

5.5 Biomarkers

A biomarker is an objectively measurable characteristic that represents an indicator of normal and pathological biological processes or an indicator of pharmacological response following a therapeutic intervention [31].

The identification of biomarkers linked to pathologies makes it possible to collect a large number of data that are useful for determining chronobiological trends. It is by submitting this data to a dynamic analysis in bioinformatics that the medicine will be able to propose diagnosis and prognosis of great precision which is always more personalized.

Wehling et al. describe the discovery and analysis of biomarkers as the most appropriate field of research to assist clinical medicine [32]. Biomarkers can collect measurements of different physiological activities for the benefit of their interpretations under pathological conditions [33].

Many factors can affect biomarker values. To ensure the sensitivity and specificity of biomarker evaluation, systems biology methods integrating translational bioinformatics and data processing strategies have been developed. The goal of identifying new biomarkers is to support the medical decision. Indeed, it is through the identification of more accurate and robust biomarkers or the identification of groups of biomarkers that tomorrow’s physicians will be better able to study the many multidimensional factors of health dynamics.

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